One of Sims' longest running YouTube series was the '100 Baby Challenge' series, in which she completed the 100 Baby Challenge in The Sims 4 over the course of five years. In 2019, for her 'Simsie Save', in which Sims renovates the game's worlds and characters, Sims made all toilets in her save gender-neutral. Sims is the creator of the Wolf Pack Challenge, which uses The Sims 4: Cats & Dogs expansion pack, and the Not So Berry Challenge, created with her friend Zoë (alwaysimming). As of July 2023, Sims has over 1.9 million subscribers. Sims' most popular YouTube video, 'Building in The Sims but Each Room is a Different Budget' has over 4 million views. Sims started making YouTube videos about The Sims in 2015.
Sims is best known for playing The Sims 4, collaborations with EA on projects such as The Sims 4: Snowy Escape and The Sims 4: Growing Together, and her charity work for St. Kayla Marie Sims (born August 14, 1999), also known by her YouTube handle lilsimsie, is an American YouTuber and Twitch streamer.